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I had the same question and searched everywhere and none of the manufacturers said they were pre-gapped. But if you search for a pre-gapped plug they all make sure to mention it so I'm going to go out on a limb and say no, you have to gap them to spec. Which is .044 with about .02 play room.
So finally got a good answer on this issue, called up my friend that works for Nissan and he told me laser iridium plugs use the same gap across pretty much every car. They double check the gap before installing it but they don't gap the plugs. So either one you buy will be fine.